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Complementary techniques for biophysical characterization of peptides and protein-based drug products

By December 4th, 2024No Comments

WEBINAR

20th November 2024 15:00–16:00 CET

Complementary techniques for biophysical characterization of peptides and protein-based drug products

About the event

In early research and development of peptide and new protein- based drug products, the combination of biophysical and structural properties is used to inform rational design of stable pharmaceutical formulation. In this webinar, we will share how Small angle X-ray scattering (SAXS) complemented with other scattering methods allows detailed investigation of protein and peptide behaviour across various sample conditions, and can be used to inform triaging of lead candidates or to optimise formulation conditions.
Sign in and learn how Novo Nordisk is combining Dynamic Light Scattering (DLS) with Small Angle X-ray Scattering (SAXS) and Size-Exclusion Chromatography Multi-Angle Light Scattering (SEC-MALS) to better understand peptide population distribution and study agglomeration.

Who should attend?

Scientists and researchers interested in stability of biopharmaceuticals, such as peptides.

What will you learn?

Learn how to better understand peptide population distributions and agglomeration tendencies Understand how SAXS and SEC-MALS can overcome the limitations of DLS, particularly in studying peptide aggregation and distribution across different populations.

Presented by:

Alina Kulakova Almind, PhD, is a Senior Research Scientist in Biophysics and Formulation in Early Research and Development at Novo Nordisk. She earned her PhD from the Technical University of Denmark, where she specialized in Biophysics, with focus on Small Angle X-ray Scattering (SAXS). After completing two Postdoctoral Fellowships in the same field, she joined Novo Nordisk, where she has been involved in supporting the early pipeline with biophysical characterization of proteins and peptides, utilizing various biophysical methods.
Sren Skou, PhD, is the Managing Director of Xenocs Nordic in Denmark, where he leads Xenocs developments in the biological and pharmaceutical sectors. He got his Ph.D. at the Technical University of Denmark in the field of Biophysics and Small Angle X-ray Scattering (SAXS) and did two Post Docs, one of which was at the BioSAXS beamline at the Cornell High Energy Synchrotron Source in the US which included work with microfluidics and sample automation for biological samples. Soren has been engaged in the SAXS industry for more than 11 years with experience in both instrument design and development as well as sales and business development for biological applications of SAXS.

Hanna Jankevics-Jones, PhD, is Sector Marketing Director Pharma & Food at Malvern Panalytical. She studied Physics at the Royal institute of technology (Stockholm, Sweden) followed by a PhD in Physical Chemistry obtained obtained from the Swiss federal institute of technology Lausanne (Switzerland). Hanna joined Malvern Instruments in 2008 as a Product Technical Specialist for biophysical characterization. Over the years, she has played a key role in various initiatives and is now the Sector Marketing Director for Pharma & Food at Malvern Panalytical.

Xenocs and Malvern Panalytical Collaboration

Learn more on Xenocs and Malvern Panalytical Collaboration here.