Barandiaran, I.; Grana, E.; Katsigiannopoulos, D.; Avgeropoulos, A.; Kortaberria, G.
Nanocomposites based on nanostructured PI-b-PMMA copolymer and selectively placed PMMA-modified magnetic nanoparticles: Morphological and magnetic characterization
European Polymer Journal, 2016, vol 75pp. 514–524DOI:Visit the full articleBack to the overview
Twist-bend nematics, liquid crystal dimers, structure–property relations
Dawood, Alya A.; Grossel, Martin C.; Luckhurst, Geoffrey R.; Richardson, Robert M.; Timimi, Bakir A.; Wells, Neil J.; Yousif, Yousif Z.
One of the current challenges in liquid crystal science is to understand the molecular factors leading to the formation of the intriguing twist-bend nematic phase (NTB) and determine its properties. During our earlier hunt for the NTB phase created on cooling directly from the isotropic phase and not the nematic…
Relationship between Side-Chain Polarity and the Self-Assembly Characteristics of Perylene Diimide Derivatives in Aqueous Solution
Schill, Jurgen; Milroy, Lech-Gustav; Lugger, Jody A. M.; Schenning, Albertus P. H. J.; Brunsveld, Luc
Perylene-3,4,9,10-tetracarboxylic acid diimides (PDIs) have recently gained considerable interest for water-based biosensing applications. PDIs have been studied intensively in the bulk state, but their physical properties in aqueous solution in interplay with side-chain polarity are, however, poorly understood. Therefore, three perylene diimide based derivatives were synthesized to study the…
Kinetic influence of siliceous reactions on structure formation of mesoporous silica formed via the co-structure directing agent route
Lin, Ruiyu; Carlström, Göran; Dat Pham, Quoc; Anderson, Michael W.; Topgaard, Daniel; Edler, Karen J.; Alfredsson, Viveka
Journal of Physical Chemistry C, 2016, vol 120, 7, pp. 3814–3821DOI:Visit the full articleBack to the overview
Characterization of Lipid-Based Hexosomes as Versatile Vaccine Carriers
Rodrigues, Letícia; Kyriakos, Konstantinos; Schneider, Fabian; Dietz, Hendrik; Winter, Gerhard; Papadakis, Christine M.; Hubert, Madlen
Subunit vaccines typically show insufficient immunogenicity. To address this issue, we developed a novel self-adjuvanting particulate carrier system based upon the lipids phytantriol (Phy) and mannide monooleate (MaMo). Phy is a lipid known to form nonlamellar phases in fully hydrated systems, whereas MaMo has been found to promote immune responses…
Cubosomes for in vivo fluorescence lifetime imaging
Biffi, Stefania; Andolfi, Laura; Caltagirone, Claudia; Garrovo, Chiara; Falchi, Angela M.; Lippolis, Vito; Andrea Lorenzon; Macor, Paolo; Meli, Valeria; Monduzzi, Maura; Obiols-Rabasa, Marc; Petrizza, Luca; Luca Prodi; Rosa, Antonella; Schmidt, Judith; Talmon, Yeshayahu; Murgia, Sergio
Herein we provided the first proof of principle for in vivo fluorescence optical imaging application using monoolein-based cubosomes in a healthy mouse animal model. This formulation, administered at a non-cytotoxic concentration, was capable of providing both exogenous contrast for NIR fluorescence imaging with very high efficiency and chemospecific information upon…
Theranostic hexosomes for cancer treatments: an in vitro study
Meli, Valeri; Caltagirone, Claudia; Sinico, Chiara; Lai, Francesco; Falchi, Angela M.; Monduzzi, Maura; Obiols-Rabasa, Marc; Picci, Giacomo; Rosa, Antonella; Schmidt, Judith; Talmon, Yeshayahu; Murgia, Sergio
We have formulated and investigated innovative lipid-based nanoparticles characterized by a reverse hexagonal liquid crystalline inner structure (hexosomes). These nanoparticles were doped with a potent, highly water insoluble anticancer drug, namely docetaxel, and stabilized by a mixture of commercial and folate- and rhodamine-conjugated Pluronic F108. Thus, they simultaneously possess…
Reversibly Actuating Solid Janus Polymeric Fibers
Ionov, Leonid; Stoychev, Georgi; Jehnichen, Dieter; Sommer, Jens Uwe
It is commonly assumed that the substantial element of reversibly actuating soft polymeric materials is chemical cross-linking, which is needed to provide elasticity required for the reversible actuation. On the example of melt spun and three-dimensional printed Janus fibers, we demonstrate here for the first time that cross-linking is not…
Effect of hydration and dehydration on the properties of SBA-15 layer studied by humidity scanning QCM-D
Znamenskaya, Yana; Björklund, Sebastian; Kocherbitov, Vitaly; Alfredsson, Viveka
Surface deposited layers of mesoporous silica particles could function as support for bio-sensing or drug release applications. It is crucial to control the surface deposition process and employ relevant techniques to characterize the properties of the particles on the surface. Here, we deposit SBA-15 particles on native silica or cationic…
Composition and structure of high temperature dairy fouling
Hagsten, Carin; Altskär, Annika; Gustafsson, Stefan; Lorén, Niklas; Hamberg, Lars; Innings, Fredrik; Paulsson, Marie; Nylander, Tommy
The fouling structure and composition is dependent on the product, but also on the heating process applied to it. The structure will have profound effect on the cleaning process and the down time in the production plant. Here, the structure of high temperature (137 °C) milk fouling has been investigated,…