Kumar, Raj; Dhasaiyan, Prabhu; Naveenkumar, Parinamipura M.; Sharma, Kamendra P.
A solvent-free porous liquid comprising hollow nanorodpolymer surfactant conjugates
Liquids having permanent porosity can offer significant processing advantages over their solid counterparts. This has recently led to tremendous activity towards the design and development of intrinsic pores in the liquid phase, predominantly for studies involving gas sequestration. We show here the development of a solvent-free mesoporous liquid material based…
Enhancing the accessibility to basic sites of as-synthesized silicas applied in catalytic transesterification
Zapelini, Iago W.; Silva, Laura L.; Oliveira, Cristiano L. P.; Cardoso, Dilson
Heterogeneous catalysis for biodiesel production is a current challenge due to the low activity of solid catalysts, especially caused by diffusional resistances. Hybrid silicas, containing SiO?CTA+ provide high conversions in the transesterification of oils and model molecules, but this activity is limited to the external surface area. The generation of…
Development and characterization of a novel soy lecithin-stearic acid and whey protein concentrate bigel system for potential edible applications
Bollom, Mark A.; Clark, Stephanie; Acevedo, Nuria C.
Bigels are a new technology with great potential in the food industry. Their success with drug delivery suggests they may be able to deliver sensitive compounds in foods, such as probiotics and bioactives. The purpose of this study was to develop and characterize a novel, edible bigel system. The bigel…
Aescin-Induced Conversion of Gel-Phase Lipid Membranes into Bicelle-like Lipid Nanoparticles
Geisler, Ramsia; Pedersen, Martin Cramer; Hannappel, Yvonne; Schweins, Ralf; Prévost, Sylvain; Dattani, Rajeev; Arleth, Lise; Hellweg, Thomas
Mixtures of the phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and the saponin ?-aescin spontaneously form monodisperse, bilayered discoidal micelles (also known as bicelles or nanodisks) in aqueous solution. Such bicelles form below the melting temperature of DMPC when the phospholipids are in the rigid L?? state and are precursors of spontaneously formed vesicles.…
Characterization of phospholipid vesicles containing lauric acid: physicochemical basis for process and product development
Farkuh, Laura; Hennies, Paulo T.; Nunes, Cláudia; Reis, Salette; Barreiros, Luisa; Segundo, Marcela A.; Oseliero Filho, Pedro L.; Oliveira, Cristiano L. P.; Cassago, Alexandre; Portugal, Rodrigo V.; Muramoto, Rodrigo A.; Carretero, Gustavo P. B.; Schreier, Shirley; Chaimovich, Hernan; Cuccovia, Iolanda M.
Lauric acid (LAH) strongly inhibits the growth of acne-causing bacteria. LAH is essentially water-insoluble and the solubility of laurate (LA) salts are medium and temperature dependent. Hence, LAH/LA preparations are difficult to formulate. Here we fully characterized phospholipid vesicles containing up to 50 mol% LAH. Vesicles of dipalmitoylphosphatidylcholine (DPPC) containing…
Rapid Stabilization of Immiscible Fluids using Nanostructured Interfaces via Surfactant Association
Niroobakhsh, Zahra; LaNasa, Jacob A.; Belmonte, Andrew; Hickey, Robert J.
Surfactant molecules have been extensively used as emulsifying agents to stabilize immiscible fluids. Droplet stability has been shown to be increased when ordered nanoscale phases form at the interface of the two fluids due to surfactant association. Here, we report on using mixtures of a cationic surfactant and long chained…
The structure of spray-dried detergent powders
Farshchi, Amin; Hassanpour, Ali; Bayly, Andrew E.
The complex multiscale structure of spray dried detergent granules has been characterized using a complementary range of techniques including scanning electron microscopy (SEM), image analysis, wide angle and small angle X-ray scattering (WAXS, SAXS) and X-ray microtomography. A complex composite structure is revealed due to the multiphase nature of the…
Self-Assembly of the Bio-Surfactant Aescin in Solution: A Small-Angle X-ray Scattering and Fluorescence Study
Dargel, Carina; Geisler, Ramsia; Hannappel, Yvonne; Kemker, Isabell; Sewald, Norbert; Hellweg, Thomas
This work investigates the temperature-dependent micelle formation as well as the micellar structure of the saponin aescin. The critical micelle concentration ( cmc ) of aescin is determined from the concentration-dependent autofluorescence (AF) of aescin. Values between cmcaescin,AF (10°C) = 0.38 ± 0.09 mM and cmcaescin,AF (50°C) = 0.32 ±…
Deoxycholic acid and l-Phenylalanine enrich their hydrogel properties when combined in a zwitterionic derivative
Travaglini, Leana; di Gregorio, Maria Chiara; Severoni, Emilia; D’Annibale, Andrea; Sennato, Simona; Tardani, Franco; Giustini, Mauro; Gubitosi, Marta; Del Giudice, Alessandra; Galantini, Luciano
Hypothesis Sodium Deoxycholate (NaDC) and Phenylalanine (Phe) are important biological hydrogelators. NaDC hydrogels form by lowering the pH or by increasing the ionic strength. Phe gels form from saturated solution by thermal induction and slow kinetics. The resulting gels hold great potential in medicine and biology as drug carriers and…
Block copolymers as bile salt sequestrants: intriguing structures formed in a mixture of an oppositely charged amphiphilic block copolymer and bile salt
Schillén, Karin; Galantini, Luciano; Du, Guanqun; Del Giudice, Alessandra; Alfredsson, Viveka; Carnerup, Anna M.; Pavel, Nicolae V.; Masci, Giancarlo; Nyström, Bo
To study the formation and characterize the structure of mixed complexes of oppositely charged block copolymers and surfactants are of great significance for practical applications, e.g., in drug carrier formulations that are based on electrostatically assisted assembly. In this context, biocompatible block copolymers and biosurfactants (like bile salts) are particularly…