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Paticle size distribution
Size distribution of nanoparticles: powders, dispersions and composites Application notes

Size distribution of nanoparticles: powders, dispersions and composites

Size distributions of industrial nanoparticles have been determined in various forms for quality assessment and process monitoring. Nanoparticles are being produced at an increasing rate and have become an essential building block for the development of new materials with improved properties. The performance of the final products depends not only…
Vesicles SAXS
Vesicles Application notes

Vesicles

Probing the effect of oxidation on model lipid bilayers The vital function of cells depends strongly on cell membranes which enclose cellular compartments and separate the cell interior from the extracellular domain. Oxidative stress for example damages the cell membrane and is at the origin of many pathological conditions such…
Microgels
Microgels Application notes

Microgels

Screening of stimuli-responsive colloidal particles Microgels are colloidal particles consisting of cross-linked 3-dimensional polymer networks. These particles have the ability to shrink or swell substantially in response to external stimuli such as temperature, pH, ionic strength and light, allowing triggered release of encapsulated bioactive molecules. They additionally protect these loaded…
Thorough investigation of oligomers during protein fibrillation Application notes

Thorough investigation of oligomers during protein fibrillation

The transient nature of aggregates during the fibrillation process of α-synuclein is highlighted with in-house SAXS experiments using the BioXolver. Protein aggregation into fibrillar structures is associated with a variety of neurodegenerative disorders, such as Parkinson’s and Alzheimer’s diseases. It is becoming increasingly evident that the toxic species causing the…
In-lab SEC-SAXS for structural investigation of complex samples Application notesApplication notes-Pharma

In-lab SEC-SAXS for structural investigation of complex samples

How to study the structure of complex biological samples? High quality data and 3D envelopes can be obtained on small and large proteins with SEC-SAXS in the lab Small-angle X-ray scattering (SAXS) is commonly used to investigate the solution structure of biological macromolecules. Highly accurate results can be obtained with…