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A designer peptide as a template for growing Au nanoclusters

la Rica, Robertoáde; ThomasáPashuck, E.; others

Customer publications

A designer peptide as a template for growing Au nanoclusters

la Rica, Robertoáde; ThomasáPashuck, E.; others

A peptide was designed to generate a sub-nanometric template that guides the growth of fluorescent gold nanoclusters. The peptide was endorsed with nucleating moieties and a three-dimensional structure that arrests the growth of ultrasmall nanoparticles. The nanoclusters are not cytotoxic and can be found in the cytosol of…
The Effect of Protein PEGylation on Physical Stability in Liquid Formulation

Holm, Louise Stenstrup; Mcumber, Aaron; Rasmussen, Jakob Ewald; Obiols-Rabasa, Marc; Thulstrup, Peter W.; Kasimova, Marina R.; Randolph, Theodore W.; van de Weert, Marco

Customer publications

The Effect of Protein PEGylation on Physical Stability in Liquid Formulation

Holm, Louise Stenstrup; Mcumber, Aaron; Rasmussen, Jakob Ewald; Obiols-Rabasa, Marc; Thulstrup, Peter W.; Kasimova, Marina R.; Randolph, Theodore W.; van de Weert, Marco

The presence of micron aggregates in protein formulations has recently attracted increased interest from regulatory authorities, industry, and academia because of the potential undesired side effects of their presence. In this study, we characterized the micron aggregate formation of hen egg-white lysozyme (Lyz) and its diPEGylated (5 kDa) analog as…
Interactions of Small Dendrimers with Sodium Dodecyl Sulfate at the Air–Water Interface

Yanez Arteta, Marianna; Campbell, Richard A.; Watkins, Erik B.; Obiols-Rabasa, Marc; Schillén, Karin; Nylander, Tommy

Customer publications

Interactions of Small Dendrimers with Sodium Dodecyl Sulfate at the Air–Water Interface

Yanez Arteta, Marianna; Campbell, Richard A.; Watkins, Erik B.; Obiols-Rabasa, Marc; Schillén, Karin; Nylander, Tommy

We have determined how the bulk behavior of mixtures of small cationic poly(amidoamine) dendrimers (generation 2, PAMAM-G2) and sodium dodecyl sulfate (SDS) affects the structure and composition of the adsorbed layers at the air?water interface. The aim is to reveal how the size of a well-defined hyperbranched polyelectrolyte affects the…
Water-Insoluble Surface Coatings of Polyion–Surfactant Ion Complex Salts Respond to Additives in a Surrounding Aqueous Solution

Gustavsson, Charlotte; Obiols-Rabasa, Marc; Piculell, Lennart

Customer publications

Water-Insoluble Surface Coatings of Polyion–Surfactant Ion Complex Salts Respond to Additives in a Surrounding Aqueous Solution

Gustavsson, Charlotte; Obiols-Rabasa, Marc; Piculell, Lennart

Hydrated, but water-insoluble, ?complex salts? (CS) composed of alkyltrimethylammonium surfactant ions with polyacrylate counterions are known to exhibit a rich phase behavior in bulk mixtures with water and have recently been shown to act as water-responsive surface coatings. Here it is shown, by SAXS measurements, that surface coatings of CS…
Tailoring Supramolecular Nanotubes by Bile Salt Based Surfactant Mixtures

Gubitosi, Marta; Travaglini, Leana; di Gregorio, Maria Chiara; Pavel, Nicolae V.; Vázquez Tato, José; Sennato, Simona; Olsson, Ulf; Schillén, Karin; Galantini, Luciano

Customer publications

Tailoring Supramolecular Nanotubes by Bile Salt Based Surfactant Mixtures

Gubitosi, Marta; Travaglini, Leana; di Gregorio, Maria Chiara; Pavel, Nicolae V.; Vázquez Tato, José; Sennato, Simona; Olsson, Ulf; Schillén, Karin; Galantini, Luciano

An approach for tailoring self-assembled tubular structures is described. By controlling the relative composition of a two-component surfactant mixture comprising the natural bile salt lithocholate and its bolamphiphilic derivative, it was possible to finely tune the nanotube cross-section of the mixed tubular aggregates that self-associated spontaneously in aqueous solution at…
Multi stimuli response of a single surfactant presenting a rich self-assembly behavior

Gregorio, M. C. di; Varenik, M.; Gubitosi, M.; Travaglini, L.; Pavel, N. V.; Jover, A.; Meijide, F.; Regev, O.; Galantini, L.

Customer publications

Multi stimuli response of a single surfactant presenting a rich self-assembly behavior

Gregorio, M. C. di; Varenik, M.; Gubitosi, M.; Travaglini, L.; Pavel, N. V.; Jover, A.; Meijide, F.; Regev, O.; Galantini, L.

This work reports on the multi stimuli sensitivity of a cholic acid derivative in a buffer. The molecules self-organize in single walled tubules at room temperature and pH 8.0–9.5. By increasing the pH to 10.0–12.0, these tubules open up and form scrolls, which transform by aging into different tubular structures.…
Lithium-Salt-Containing High-Molecular-Weight Polystyrene-block-Polyethylene Oxide Block Copolymer Films

Metwalli, Ezzeldin; Rasool, Majid; Brunner, Simon; Müller-Buschbaum, Peter

Customer publications

Lithium-Salt-Containing High-Molecular-Weight Polystyrene-block-Polyethylene Oxide Block Copolymer Films

Metwalli, Ezzeldin; Rasool, Majid; Brunner, Simon; Müller-Buschbaum, Peter

Ionic conductivity in relation to the morphology of lithium-doped high-molecular-weight polystyrene-block-polyethylene oxide (PS-b-PEO) diblock copolymer films was investigated as solid-state membranes for lithium-ion batteries. The tendency of the polyethylene (PEO) block to crystallize was highly suppressed by increasing both the salt-doping level and the temperature. The PEO crystallites…