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Monodisperse Cylindrical Micelles and Block Comicelles of Controlled Length in Aqueous Media

Nazemi, Ali; Boott, Charlotte E.; Lunn, David J.; Gwyther, Jessica; Hayward, Dominic W.; Richardson, Robert M.; Winnik, Mitchell A.; Manners, Ian

Customer publications

Monodisperse Cylindrical Micelles and Block Comicelles of Controlled Length in Aqueous Media

Nazemi, Ali; Boott, Charlotte E.; Lunn, David J.; Gwyther, Jessica; Hayward, Dominic W.; Richardson, Robert M.; Winnik, Mitchell A.; Manners, Ian

Cylindrical block copolymer micelles have shown considerable promise in various fields of biomedical research. However, unlike spherical micelles and vesicles, control over their dimensions in biologically relevant solvents has posed a key challenge that potentially limits in depth studies and their optimization for applications. Here, we report the preparation of…
Mesoporous tertiary oxides via a novel amphiphilic approach

Bennett, Natasha; Seddon, Annela M.; Hallett, James E.; Kockelmann, Winfried; Ting, Valeska P.; Sadasivan, Sajanikumari; Tooze, Robert P.; Hall, Simon R.

Customer publications

Mesoporous tertiary oxides via a novel amphiphilic approach

Bennett, Natasha; Seddon, Annela M.; Hallett, James E.; Kockelmann, Winfried; Ting, Valeska P.; Sadasivan, Sajanikumari; Tooze, Robert P.; Hall, Simon R.

We report a facile biomimetic sol-gel synthesis using the sponge phase formed by the lipid monoolein as a structure-directing template, resulting in high phase purity, mesoporous dysprosium- and gadolinium titanates. The stability of monoolein in a 1,4-butanediol and water mixture complements the use of a simple sol-gel metal oxide synthesis…
Docetaxel-Loaded Fluorescent Liquid-Crystalline Nanoparticles for Cancer Theranostics

Meli, Valeria; Caltagirone, Claudia; Falchi, Angela M.; Hyde, Stephen T.; Lippolis, Vito; Monduzzi, Maura; Obiols-Rabasa, Marc; Rosa, Antonella; Schmidt, Judith; Talmon, Yeshayahu; Murgia, Sergio

Customer publications

Docetaxel-Loaded Fluorescent Liquid-Crystalline Nanoparticles for Cancer Theranostics

Meli, Valeria; Caltagirone, Claudia; Falchi, Angela M.; Hyde, Stephen T.; Lippolis, Vito; Monduzzi, Maura; Obiols-Rabasa, Marc; Rosa, Antonella; Schmidt, Judith; Talmon, Yeshayahu; Murgia, Sergio

Here, we describe a novel monoolein-based cubosome formulation engineered for possible theranostic applications in oncology. The Docetaxel-loaded nanoparticles were stabilized in water by a mixture of commercial Pluronic (poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer) F108 (PF108) and rhodamine- and folate-conjugated PF108 so that the nanoparticles possess…
Bio-based barrier materials

Kleppinger, Ralf; Martens, Hans; Tandler, Renate; Soliman, Maria

Customer publications

Bio-based barrier materials

Kleppinger, Ralf; Martens, Hans; Tandler, Renate; Soliman, Maria

Multilayered polyolefin-based film systems are being used in packaging industry to add various functionalities by tailoring layer sequences, thickness and type of the material used in the final application. A new concept based on carbohydrates had been investigated and confirmed that similar functionality may be obtained compared to EVOH which…
Die-drawn HDPE pipes: Crystalline and Lamellae Orientation

Kleppinger, Ralf; Taraiya, Ajay; Handstanger, Ralph; Soliman, Maria

Customer publications

Die-drawn HDPE pipes: Crystalline and Lamellae Orientation

Kleppinger, Ralf; Taraiya, Ajay; Handstanger, Ralph; Soliman, Maria

It is well known that mechanical properties of isotropic polymer systems, such as tensile modulus and strength, can be considerably improved by orientation of chain molecules. This can be achieved by deforming the polymer in the solid-state via die-drawing, resulting in orientation in tow rather than one direction only, resulting…