Ivanko, Iryna; Pánek, Ji?í; Svoboda, Jan; Zhigunov, Alexander; Tomík, Elena
Tuning the photoluminescence and anisotropic structure of PEDOT
In the current work, we study the photoluminescence and anisotropic structure of PEDOT which is obtained in the presence of ions that perturb the water structure (ions in Hofmeister series). The water content in PEDOT has been confirmed by TGA and DSC measurements. The weight loss and heat flux together…
The role of disaccharides for proteinprotein interactions a SANS study
Olsson, Christoffer; Swenson, Jan
The disaccharide trehalose has shown outstanding anti-aggregation properties for proteins, which are highly important for the possibility to treat neurodegenerative diseases, such as Alzheimers and Huntingtons disease. However, the role and mechanism of trehalose for such stabilising effects are still largely unknown, partly because a direct structural picture of how…
X-ray Scattering and Coarse-Grained Simulations for Clustering and Interactions of Monoclonal Antibodies at High Concentrations
Dear, Barton J.; Bollinger, Jonathan A.; Chowdhury, Amjad; Hung, Jessica J.; Wilks, Logan R.; Karouta, Carl A.; Ramachandran, Kishan; Shay, Tony Y.; Nieto, Maria P.; Sharma, Ayush; Cheung, Jason K.; Nykypanchuk, Dmytro; Godfrin, P. Douglas; Johnston, Keith P.; Truskett, Thomas M.
Attractive proteinprotein interactions (PPI) in concentrated monoclonal antibody (mAb) solutions may lead to reversible oligomers (clusters) that impact colloidal stability and viscosity. Herein, the PPI are tuned for two mAbs via the addition of arginine (Arg), NaCl, or ZnSO4 as characterized by the structure factor (Seff(q)) with small-angle X-ray scattering…
The influence of pH, protein concentration and calcium ratio on the formation and structure of nanotubes from partially hydrolyzed bovine ?-lactalbumin
Geng, XiaoLu; Kirkensgaard, Jacob Judas Kain; Arleth, Lise; Otte, Jeanette; Ipsen, Richard
Formation of nanotubes from partially hydrolysed ?-lactalbumin (?-La) was investigated at five pH values, two concentrations of ?-La and two calcium levels. Nanotubes were formed under almost all combinations of the investigated factors, and for the first time the formation of nanotubes at low pH (4.0) and low protein concentration…
Comprehensive Investigation and Analysis of Bulk-Heterojunction Microstructure of High-Performance PCE11:PCBM Solar Cells
Zhang, Chaohong; Heumueller, Thomas; Gruber, Wolfgang; Almora, Osbel; Du, Xiaoyan; Ying, Lei; Chen, Junwu; Unruh, Tobias; Cao, Yong; Li, Ning; Brabec, Christoph J.
Worldwide research efforts have been devoted to organic photovoltaics in the hope of a large-scale commercial application in the near future. To meet the industrial production requirements, organic photovoltaics that can reach power conversion efficiency (PCE) of over 10% along with promising operational device stability are of utmost interest. In…
Harnessing Heat Beyond 200 °C from Unconcentrated Sunlight with Nonevacuated Transparent Aerogels
Zhao, Lin; Bhatia, Bikram; Yang, Sungwoo; Strobach, Elise; Weinstein, Lee A.; Cooper, Thomas A.; Chen, Gang; Wang, Evelyn N.
Heat at intermediate temperatures (120-220 °C) is in significant demand in both industrial and domestic sectors for applications such as water and space heating, steam generation, sterilization, and other industrial processes. Harnessing heat from solar energy at these temperatures, however, requires costly optical and mechanical components to concentrate the dilute…
Pure PEDOT:PSS hydrogels
Lu, Baoyang; Yuk, Hyunwoo; Lin, Shaoting; Jian, Nannan; Qu, Kai; Xu, Jingkun; Zhao, Xuanhe
Hydrogels of conducting polymers provide an electrical interface with biological tissues for sensing and stimulation, but currently have compromised mechanical and electrical properties. Here, the authors show a simple method to achieve pure PEDOT:PSS hydrogels that exhibit superior mechanical and electrical properties, stability, and tunable
Controlling Crystal Texture in Programmable Atom Equivalent Thin Films
Gabrys, Paul A.; Macfarlane, Robert J.
DNA is a powerful tool in the directed assembly of nanoparticle based superlattice materials, as the predictable nature of WatsonCrick base pairing allows DNA-grafted particles to be programmably assembled into unit cells that arise from the complete control of nanoparticle coordination environment within the lattice. However, while the local environment…
Effects of artepillin C on model membranes displaying liquid immiscibility
Pazin, W. M.; Vilanova, N.; Voets, I. K.; Soares, A. E. E.; Ito, A. S.
It has been hypothesized that the therapeutic effects of artepillin C, a natural compound derived from Brazilian green propolis, are likely related to its partition in the lipid bilayer component of biological membranes. To test this hypothesis, we investigated the effects of the major compound of green propolis, artepillin C,…
Sulfo-Phenylated Polyphenylenes Containing Sterically Hindered Pyridines
Xu, Shaoyi; Adamski, Michael; Killer, Miho; Schibli, Eric M.; Frisken, Barbara J.; Holdcroft, Steven
We systematically investigated the effect of incorporating a sterically hindered pyridyl group into a sulfo-phenylated polyphenylene to control the polymers physicochemical properties through acidbase interactions. Homopolymers with similar molecular weights and comparable structures that vary by only one atom (N vs C?) per repeat unit along the polymer chain were…