Ma, Ya-Ping; Zheng, Wei-Ping; Liu, Chen-Guang; Shao, Hua-Feng; Nie, Hua-Rong; He, Ai-Hua
Differential Polymorphic Transformation Behavior of Polybutene-1 with Multiple Isotactic Sequences
For the solid-solid transformation from form II to form I of isotactic polybutene-1 (iPB), the temperature dependence of form I nucleation and growth was deemed to control the transformation process. However, the relationship between form I formation and form II disappearance in the transformation process is not clear. In this…
Improvement of Antialveolar Echinococcosis Efficacy of Albendazole by a Novel Nanocrystalline Formulation with Enhanced Oral Bioavailability
Hu, Chunhui; Liu, Zhengsheng; Liu, Chengyu; Zhang, Yaogang; Fan, Haining; Qian, Feng
Alveolar echinococcosis (AE) is a chronic infectious parasitic disease that is fatal and still being neglected. Currently, the AE treatment recommended by the WHO is complete excision of the lesions, followed by the oral administration of albendazole (ABZ), the only effective first-line anti-AE drug, for two years. Unfortunately, complete excision…
Preparation and liquid crystal phase properties of discotic cellulose nanoparticles
Li, Chenxi; Evans, Julian; Wang, Nan; Guo, Tingbiao; He, Sailing
Understanding the behavior of fluids with inhomogeneous structural properties is critical for many industrial and biological materials. Sulfuric acid hydrolysis of cotton with ultrasonic treatment and low-speed centrifugation during purification yields spiky discotic cellulose particles. Amorphous cellulose remained in solution and forms discotic units which may be nucleated by crystalline
Chirality Transfer in Coassembled Organogels Enabling Wide-Range Naked-Eye Enantiodifferentiation
Yue, Bingbing; Yin, Liyuan; Zhao, Wandong; Jia, Xiaoyong; Zhu, Mingjie; Wu, Bin; Wu, Si; Zhu, Liangliang
Enantiodifferentiation is crucial in organic chemistry, pharmacochemistry, material chemistry, and life science. However, it remains tremendously challenging to achieve a broad enantioselectivity to different types of chiral substrates via a single-material design. Here, we report a coassembled organogel strategy with chirality transfer to make an enantioselective generality possible. This
Distinguishing Between Monomeric scFv and Diabody in Solution Using Light and Small Angle X-ray Scattering
Lüdel, Frank; Bufe, Sandra; Bleymüller, Willem M.; de Jonge, Hugo; Iamele, Luisa; Niemann, Hartmut H.; Hellweg, Thomas
Depending on the linker length between the V H and the V L domain, single-chain Fv (scFv) antibody fragments form monomers, dimers (diabodies) or higher oligomers. We aimed at generating a diabody of the anti-MET antibody 3H3 to use it as crystallization chaperone to promote crystallization of the MET ectodomain…
Crystallization of forms I? and form II of polybutene-1 in stretched polypropylene/polybutene-1 blends
Xu, Yao; Ma, Yaping; Liu, Chenguang; Men, Yongfeng; He, Aihua
In this work, the effects of orientated crystal morphology of polypropylene (PP) induced by tensile stretching on the subsequent crystallization behavior of polybutene-1 (PB-1) in the incompatible PP/PB-1 (50/50) blends were studied. When the PP/PB-1 blends were stretched at a temperature above melting temperature (Tm) of PB-1 but below the…
Highly Stretchable Photonic Crystal Hydrogels for a Sensitive Mechanochromic Sensor and Direct Ink Writing
Chen, Jiayao; Xu, Lirong; Yang, Meijia; Chen, Xiaochuan; Chen, Xudong; Hong, Wei
Photonic crystals, which are materials with periodic dielectric constants on the submicroscale, have been the focus of research for an extended period. Photonic soft materials have been extensively developed for use as colorimetric indicators and mechanochromic sensors, but their limited mechanical properties and molding characteristics only suitable for films restrict…
Moebius strips of chiral block copolymers
Geng, Zhen; Xiong, Bijin; Wang, Liquan; Wang, Ke; Ren, Min; Zhang, Lianbin; Zhu, Jintao; Yang, Zhenzhong
The Moebius topology (twisted, single-sided strip) is intriguing because of its structural elegance and distinct properties. Here we report the generation of block copolymer Moebius strips via a fast self-assembly of chiral block copolymer polystyrene-block-poly(D-lactide acid) (PS-b-PDLA) in tetrahydrofuran/water mixed solvents. The Moebius strip is formed by morphological evolution from…
Antigenic and physicochemical characterization of Hepatitis B surface protein under extreme temperature and pH conditions
Lopes, J. L. S.; Oliveira, D. C. A.; Utescher, C. L. A.; Quintilio, W.; Tenório, E. C. N.; Oliveira, C. L. P.; Fantini, M. C. A.; Rasmussen, M. K.; Bordallo, H. N.; Sant’Anna, O. A.; Botosso, V. F.
Hepatitis B virus causes acute and chronic infections in millions of people worldwide and, since 1982, a vaccine with 95% effectiveness has been available for immunization. The main component of the recombinant hepatitis B vaccine is the surface antigen protein (HBsAg). In this work, the effect of pH, ionic strength…
Preparation, Structure, and Properties of an Isotactic Polypropylene Film with Ultrahigh Content, Ordered, and Continuous ?-Transcrystallinity
Liang, Guixue; Yang, Shuo; Li, Jiang; Guo, Shaoyun
?-Transcrystallinity (?-TC) of polypropylene (PP) is a novel kind of crystal that is of significant importance. Owing to the low content, discontinuity, and random distribution of ?-TC obtained by traditional methods, there has not been significant research on this particular crystal. Thus, its formation mechanism and growth law remain unclear…